Precise, Personalized, and Preventive Psychiatry
Live. Happier. Longer.
Mental health care shouldn’t be trial and error.
One blood test reads the activity of your genes, so you and your clinician can see what is happening and choose treatments that fit your biology.
MindX One® from $1,458 · HSA/FSA accepted · at-home blood draw included
Our mission
There is no health without mental health.
Our science-based approach is built on two decades of biomarker discovery and validation research, published in leading psychiatry journals and featured in NIH Research Matters. That research is always ongoing, so people can benefit as the science advances. It helps objectively assess mental health, pain, and active longevity; match people to treatments that transform their life; and prevent future clinical episodes. So you can proceed with confidence towards optimal outcomes, and take charge of your life.
01
Assess
Objective measures of current severity and one-year risk across eight areas of mental health.
02
Match
Treatments ranked by fit with your biology, from 207 medications and 365 nutraceuticals and alternatives. Often with fewer medications.
03
Monitor
Repeat testing to track response over time and catch risk early, because gene activity changes with treatment.
- Molecular Psychiatry · 2026Next-generation precision medicine for mood disorders
- Molecular Psychiatry · 2025Next-generation precision medicine for pain
- Translational Psychiatry · 2024Next-generation precision medicine for suicidality prevention
- PublicationsAll publications
A portion of sales revenue is donated each month to mental health support organizations, currently the Wounded Warrior Project.
Life x Improve® Digital Testing is free for veterans.
Latest News
Where would you like to start?
Help for you and the people you love.
Patients & families
Worried about yourself or someone you love?
Get unstuck and optimize mental health, starting with biology. We’ll help you understand the test, the results, and the next steps with your clinician.
Clinicians
Objective data for treatment decisions.
Order MindX One for your patients and receive integrated reports in a secure portal.
Organizations & pharma
Healthier people. More reliable trials.
Population-level Life x Improve® testing, and blood biomarkers for patient selection and response.
Partners & investors
The science, the platform, the pipeline.
Patents, publications, certifications and what we are developing next, in one place.

One blood test. Eight areas of mental health.
Mood, anxiety, stress, psychosis, suicidality, pain, memory, and longevity.
- Biomarkers measured
- 356
- Medications matched
- 207
- Nutraceuticals & alternatives
- 365
- Areas of mental health
- 8
MindX One® Wellness
$1,458
MindX One® XC
$1,958
MindX One® XL
$2,958
- HSA/FSA accepted · monthly payments through CareCredit*
- Complimentary at-home blood draw
- Analyzed in our CLIA-certified laboratory
*Subject to credit approval. Deferred-interest terms per CareCredit.
How it works
- 1
Order online
Choose a package and pay by card, HSA/FSA, invoice, or monthly through CareCredit.
- 2
Blood draw at home
The blood draw is complimentary — at home, or at your doctor’s office if you prefer.
- 3
Results with your clinician
Results in 3–4 weeks, in secure portals for you and your clinician.
The MindX Comprehensive Solution
Biology, sociology, psychology, and an advisor at your side.
Products are independent of each other, but there is synergy in using them together.
Biology
MindX One® Liquid Biopsy
A blood gene expression biomarkers-based testing. It helps with objective assessment and matching to medications and nutraceuticals. This leads to precise, personalized treatment for mental health, pain, and active longevity. Oftentimes, fewer medications.
Learn moreSociology
Life x Improve® Digital Testing
Provides a score, and personalized life improvement plan. This plan leads to increased resilience, and decreases the risk for suicidality.
Learn morePsychology

Life x Mind® App
A comprehensive and easy way to help measure and manage how you feel, think, and behave. It is a daily companion for your life and your mind.
Learn moreAdvisor

MindX AI Advisor (Max)
Provides advice and insights to our clients based on the body of knowledge in the field, our proprietary knowledge over the years, and emerging insights from testing individuals. Free for patients and clinicians who use our testing. A pro subscription version is available for clinics, pharma, and organizations.
Learn moreIn their words
Real experiences from patients and clinicians.
“The results of the MindX Sciences reports have been uncannily accurate in finding the most effective treatments and for many, it is life-changing and life-saving. I cannot recommend it more highly.”
Dr. Mark Jaffe
Private Practice, Los Angeles, CA
“The MindX blood testing enabled my doctor to prescribe the right medication after multiple unsuccessful treatments. Shortly after, I started to feel significantly better and I am now fully recovered.”
I.S.
Patient, California
“Our clinic is thrilled to have access to a simple assay which moves beyond the tired and pedestrian cell-surface neuronal signaling models of psychiatric disease, e.g. "DOPAMINE!" and the like. Implications for rational polypharmacy are obvious.”
Dr. Jon Berner
Woodinville Psychiatric Associates, Woodinville, WA
“MindX Sciences has assisted Grey Matters International's toolkit in advancing patient care and patient-centric services like no other.”
Dr. Kevin Fleming
Grey Matters International, Tulsa, Oklahoma
“MindX Sciences has the most successful form of assessment and medication assignment for patients I have seen. As someone who's had a long history with trial and error when it came to medications, the efficiency and accuracy of these blood tests were spot on, and gave me incredible results to become healthier and happier.”
M.B.
Patient, Indiana
“I feel like a new person, more in control of myself and my emotions. I don't want to be flippant, but this change feels like it has given me so much. Not because everything is 'up and to the right' and I am manically happy all the time, but I can catch myself and regulate at crucial points where in the past I would fly off the handle. This is huge in so many respects.”
E.S.
Patient, Indiana
“Previous experiences from other doctors relied on a trial-and-error approach with medication that yielded limited results and sometimes had significant side effects. Seeking a more effective and personalized treatment, I met with Dr. Niculescu, who suggested the MindX test to find the right medications for my issue based on the results of a blood test. Though I was initially skeptical of the unorthodox approach, the results ended up creating a therapeutic approach tailored to my genetic profile and based upon two low-dose medications rather than a non-specific high-dose one. Having been on this therapy for a year, I can say that this medical management proved to be the most effective psychiatric help I've received so far and is the one I continue to use to this day.”
S.Y.
Patient, Indiana
“The opportunity of mRNA blood work analysis in this field with tentative diagnosis and medication/OTC recommendations made all the difference in behavioral understanding. It prompted us to seek further self-pay options that confirmed the MindX results.”
C.K.
Patient, Ohio
Individual experiences. Results vary.
















