Newsletter

Mismatch Negativity2025-07-21

For success in clinical medicine, getting the correct diagnosis, followed by the correct treatment, are key. Diagnosis and treatment are best individualized, as people are multidimensional and have different co-morbidities, environmental factors, and cultural values.

What happens when there is a mismatch between what diagnosis a person is labeled with vs. has in reality, and what treatment a person is on vs. what they should be on? We call that on my teams “mismatch negativity” (not to be confused with the technical term in electrophysiology), and it is the main reason for poor clinical care, suboptimal outcomes in psychiatry, drug development failures, and spiraling healthcare costs.

The MindX One​Blood Testing combines in one place assessment for multiple mental health conditions, and treatment for them. That is why we call it One. The Life x Improve​Digital Testing finds addressable social determinants. And the Life x Mind app helps people keep track of their minds and navigate their lives better.

Use the latest science-based insights from MindX Sciences. To help improve patient outcomes, clinical practice, drug development, and healthcare economics for organizations.